Systems Biology in Drug Discovery and Development: Methods and Protocols

Thursday, February 17, 2011

Product Details
pages: 351 pages
Publisher: Humana Press; 1st Edition (September 21, 2010)
ISBN 10: 1607617994 / 1607618001
ISBN 13: 9781607617990 / 9781607618003
Format: HQ paginated PDF with cover & multi-level bookmarks
Size: 6.76 MB
Supplier:
Summary:

Product Description
Due to the failing “one-drug-fits-all” model, it has become increasingly necessary to develop personalized medicine that treats whole systems and brings the right drug to the right patient with the right dosages. In Systems Biology in Drug Discovery and Development: Methods and Protocols, leading experts provide a practical, state-of-the-art, and holistic view of the translation of systems biology into better drug discovery and personalized medical practice. While the first part of the book describes cutting-edge technologies and methods in the field, the second part illustrates how the technologies can be applied in science for disease understanding and therapeutic discovery. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and up-to-date, Systems Biology in Drug Discovery and Development: Methods and Protocols covers topics from fundamental concepts to advanced technologies in order to best serve biomedical students and professionals at all levels who are interested in vital integrative studies in molecular biology, genetics, bioinformatics, bioengineering, biochemistry, physiology, pathology, microbiology, immunology, pharmacology, toxicology, drug discovery, and clinical medicine.

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A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics

Product Description
This book, "A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics", documents the present state of knowledge of the adenosine A3 receptor. Adenosine A3 receptors are G protein-linked receptors that function in physiology and intracellular signaling and are involved in inflammatory responses and mediating cell proliferation and cell death.

The A3 receptor is increasingly being recognized for its biological roles throughout the body, and many A3 receptor ligands have proven useful in elucidating peripheral and central pathologies. This book covers a wide range of information including data from studies of theoretical, molecular and cellular pharmacology, signal transduction, integrative physiology, new drug discoveries and clinical applications. The book includes sections on: A3 Adenosine Receptor signal transduction, adenosine Receptor medicinal chemistry, effects and therapeutic applications of Adenosine Receptors on tissues and organs, adenosine Receptors and inflammatory and auto-immune diseases, adenosine Receptors and cancer.

The chapters in this book cover both fundamental science and relevant applications and provide an authoritative account of the current status of the field. "A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics" is an up to date and scientifically excellent source of information, attractive to basic and clinical scientists alike.

Product Details
* Hardcover: 322 pages
* Publisher: Springer; 1 edition (December 17, 2009)
* Language: English
* ISBN-10: 904813143X
* ISBN-13: 978-9048131433
* Format: PDF [6.65 MB]

CODE:

http://ifile.it/hxu32cd