Natural Killer Cells: Basic Science and Clinical Application

Tuesday, February 15, 2011

• Publisher: Academic Press
• Number Of Pages: 660
• Publication Date: 2009-12-28
• ISBN-10 / ASIN: 0123704545
• ISBN-13 / EAN: 9780123704542

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The Natural Killer [NK] Cell plays a critical role in regulating the innate and adaptive immune response to pathogens, injury and stress. Although originally portrayed as primarily a lytic cell, the NK cell has emerged as a cell capable of helper function, expansion, contraction, and accelerated memory responses - features similar to other adaptive immune cells. It is a professional accelerator of immunity, mediating dendritic cell maturation and its precursors critical for the origin and development of secondary lymph node structures. NK cells also play an essential role in mammalian placentation by regulating the quality of blood supply to the growing fetus. These characteristics place the NK cell in a unique position, with a major role in sculpting the host response to damage and injury.
This volume is the first complete and authoritative reference to explore these emergent, exciting aspects of the NK cell, placing it at the center of damage/danger recognition and the response to stress. Natural Killer Cells details NK cell biology, the role of NK cells in regulating immunity through interactions with other cells and tissues, the participation of NK cells in disease and special topics in NK biology.




- Provides a broad, detailed canvas for students, fellows, scientists, and practitioners

- Includes figures, histologic sections, and illustrations of the ontogeny of NK cells

- Image database included in companion website

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Clinical Immunology and Serology: A Laboratory Perspective

• Publisher: F A Davis Co
• Number Of Pages: 454
• Publication Date: 2009-08-06
• ISBN-10 / ASIN: 080361814X
• ISBN-13 / EAN: 9780803618145

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This title is completely updated to include new information about the immune system and new treatments for immunological diseases! This practical introduction to clinical immunology covers all of the essential theoretical principles and the serology techniques most commonly used in the laboratory. Structured into easy-to-read, student-friendly sections, the 3rd edition focuses on the direct application of theory to clinical laboratory practice. The pedagogical structure for each chapter includes: chapter outlines; key terms; objectives; multiple-choice review questions with answer keys case studies; and, chapter summaries. Case studies make topics more relevant and help to explain the 'big picture'. Each chapter is a complete learning module that contains theoretic principles, illustrations, definitions of relevant terminology, procedures for simulated clinical testing, and questions and case studies that help to evaluate learning. There is an insert that features full-color slides that visually demonstrate what to expect in the lab and show the relationship between immunology and hematology. Updated references and additional lab exercises reflect changes in immunology and serology. Lab exercises are designed to illustrate and reinforce principles discussed in the chapters.

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